Sulfasalazine EP Impurity G Disodium Salt CAS 1391062-37-5 (free acid)
| CAS No. | 1391062-37-5 (free acid) |
| Molecular Formula | C29H20N6O7S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sulfasalazine EP Impurity G Disodium Salt.
As a process- or degradation-related impurity, Sulfasalazine EP Impurity G Disodium Salt (CAS 1391062-37-5 (free acid), C29H20N6O7S2Na) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Sulfasalazine EP Impurity G Disodium Salt is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 651.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H20N6O7S2 2*Na |
| Molecular Weight | 651.62 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 23.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Sulfasalazine Standards
- Sulfasalazine EP Impurity I (CAS 1310803-27-0)
- Sulfasalazine-D4 (CAS 1346606-50-5)
- Sulfasalazine Impurity 2 (RRT 0.75) (CAS 139-56-0)
- Sulfasalazine EP Impurity E (CAS 1391062-34-2)
- Sulfasalazine EP Impurity E Trisodium Salt (CAS 1391062-34-2 (free acid))
- Sulfasalazine EP Impurity A (CAS 1391062-35-3)
- Sulfasalazine EP Impurity G (CAS 1391062-37-5)
- Sulfasalazine EP Impurity G HCl (CAS 1391062-37-5 (free base))
Recommended Standards
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